HighQC™ Human iPSC-Derived Cortical GABAergic Neuron (Alzheimer’s Disease Patient, Sporadic)

Description

HighQC™ Human iPSC-Derived Cortical GABAergic Neuron (Alzheimer’s Disease Patient, Sporadic) are an advanced model for studying the mechanisms of neurodegeneration in Alzheimer’s disease, particularly focusing on GABAergic neurons in the cortex. These neurons are derived from human induced pluripotent stem cells (iPSCs) of Alzheimer’s disease patients and represent a sporadic form of the disease, which is characterized by the sporadic accumulation of amyloid plaques and tau tangles. These iPSC-derived GABAergic neurons exhibit typical cortical neuron morphology and functionality, with the ability to produce GABA (gamma-aminobutyric acid), an essential inhibitory neurotransmitter. These neurons are valuable for investigating synaptic dysfunction, neurotransmitter imbalances, and the role of GABAergic signaling in the progression of Alzheimer’s disease. As a human-relevant model, they allow researchers to explore disease mechanisms that are not easily replicated in traditional animal models. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria