HighQC Human iPSC-Derived Motor Neurons SOD1 G93A/G93A

Description

HighQC Human iPSC-Derived Motor Neurons SOD1 G93A/G93A are human iPSC-derived motor neurons generated from a human iPSC line originally derived from adult skin fibroblasts. These cryopreserved cells provide a defined in vitro model for amyotrophic lateral sclerosis (ALS) research and SOD1-associated neurodegenerative disease studies. The cells are produced through deterministic cell programming to support reproducible lineage-specific experimental systems. This line carries a homozygous SOD1 G93A missense mutation on both alleles, modeling SOD1 protein misfolding relevant to familial ALS, without implying a fixed clinical phenotype. They retain neuronal lineage characteristics associated with motor neuron models. Quality control testing includes sterility assessment and lineage characterization by protein expression and gene expression assays, where applicable. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.