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HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy, TYPE II

  • For research use only

Cat No.

ABC-SC2044
Product Type

Human iPSCs
Cell Type

Induced Pluripotent Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Fibroblast
Disease

Spinal Muscular Atrophy, TYPE II
Storage

Liquid Nitrogen

Cell Type: iPSC; Disease: Spinal Muscular Atrophy, TYPE II; SMA2.

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  • HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy, TYPE II
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Induced Pluripotent Stem Cells (iPSCs) | HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy, TYPE II

Description

HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy, TYPE II
is a disease-specific induced pluripotent stem cell line derived from dermal fibroblasts of a donor diagnosed with Spinal Muscular Atrophy (SMA) Type II, an autosomal recessive disorder caused by mutations in the SMN1 gene. These cells exhibit adherent growth and maintain the capacity for trilineage differentiation into ectoderm, mesoderm, and endoderm derivatives under appropriate conditions. These iPSCs (induced pluripotent stem cells) express the core pluripotency marker SSEA-4. They preserve SMA-related physiology and enable motor neuron function study. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy Type II, HighQC™ hiPSC SMA2, hiPSC-SMAII, HighQC™ Human Induced Pluripotent Stem Cells From Fibroblast-Spinal Muscular Atrophy Type II
Species

Human
Cat.No

ABC-SC2044
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Fibroblast
Disease

Spinal Muscular Atrophy, TYPE II
Storage

Liquid Nitrogen
Product Type

Human iPSCs
Gene Info

Gene: SMN1; Mutation: EX7-8DEL

Application

  • HighQC™ Human IPSC From Fibroblast-Spinal Muscular Atrophy, TYPE II provides a patient-specific model for in vitro developmental and disease studies. Its pluripotent capacity enables directed differentiation into motor neurons, the primary cell type affected in SMA, allowing for investigation into SMN1 gene-related pathology, motor neuron development, and disease mechanisms. This system is valuable for constructing neural organoid models to study motor circuit dysfunction and for screening potential therapeutic compounds targeting neuroprotection or SMN protein restoration.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
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