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HighQC™ Human IPSC From Foreskin Fibroblast (Fibroblasts Of A Cystic Fibrosis Patient)

  • For research use only

Cat No.

ABC-SC0016T
Product Type

Human iPSCs
Cell Type

Induced Pluripotent Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Foreskin
Disease

Fibroblasts Of A Cystic Fibrosis
Storage

Liquid Nitrogen

Deploy HighQC™ Human IPSC From Foreskin Fibroblast (Fibroblasts Of A Cystic Fibrosis Patient) to model CFTR dysfunction and test therapeutic agents.

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  • HighQC™ Human IPSC From Foreskin Fibroblast (Fibroblasts Of A Cystic Fibrosis Patient)
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Induced Pluripotent Stem Cells (iPSCs) | HighQC™ Human IPSC From Foreskin Fibroblast (Fibroblasts Of A Cystic Fibrosis Patient)

Description

HighQC™ Human iPSC From Foreskin Fibroblasts (Fibroblasts Of A Cystic Fibrosis Patient) is a type of induced pluripotent stem cell derived from foreskin fibroblasts of a patient diagnosed with cystic fibrosis (CF), a life-threatening autosomal recessive disorder caused by mutations in the CFTR gene. The cell line was generated via episomal reprogramming using a proprietary mix of vectors, containing OCT4, SOX2, KLF4, p53 antisense, and EBNA-1. It was validated for pluripotency based on classical pluripotent colony morphology, alkaline phosphatase expression, and expression of key pluripotency markers including SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ Human IPSC From Foreskin Fibroblast (Fibroblasts Of A Cystic Fibrosis Patient), Human iPSC-Fib-CF, hIPSC-Fib-CF, Human Foreskin Fibroblast Derived iPSC Cystic Fibrosis
Species

Human
Cat.No

ABC-SC0016T
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Foreskin
Disease

Fibroblasts Of A Cystic Fibrosis
Storage

Liquid Nitrogen
Product Type

Human iPSCs

Application

  • HighQC™ Human iPSC From Foreskin Fibroblasts (Fibroblasts Of A Cystic Fibrosis Patient) serves as a disease-specific in vitro model to study the pathogenesis of cystic fibrosis, particularly protein misfolding and chloride channel dysfunction associated with CFTR mutations. When differentiating these iPSCs into definitive endoderm, the developmental precursor of lung epithelium, it facilitates high-throughput drug screening, validation of CFTR modulators, and evaluation of gene correction strategies.​

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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