Stem Cells

HighQC™ Human IPSC From Foreskin Fibroblast (Morbus Niemann Pick Type C)

  • For research use only

Cat No.

ABC-SC0020T

Product Type

Human iPSCs

Cell Type

Induced Pluripotent Stem Cell

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Foreskin

Disease

Niemann Pick Type C

Storage

Liquid Nitrogen

Leverage HighQC™ Human IPSC From Foreskin Fibroblast (Morbus Niemann Pick Type C) to study NPC pathogenesis and evaluate potential therapeutic strategies.

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Description

HighQC™ Human iPSCs From Foreskin Fibroblasts (Morbus Niemann Pick Type C) is an induced pluripotent stem cell line reprogrammed from human foreskin fibroblasts of an 11-year-old male Morbus Niemann-Pick Type C patient. The cell line was generated via episomal reprogramming using a proprietary mix of vectors, containing OCT4, SOX2, KLF4, p53 antisense, and EBNA-1, preserving genomic integrity. The cell line was validated for pluripotency based on classical colony morphology, alkaline phosphatase expression, and high expression of key pluripotency markers including SSEA-4. It exhibits classical pluripotent stem cell morphology and robust growth, and can differentiate into cells/tissues of all three germ layers. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ Human IPSC From Foreskin Fibroblast (Morbus Niemann Pick Type C), Human iPSC-Fib-NPC, hIPSC-Fib-NPC, Human Foreskin Fibroblast Derived iPSC Niemann Pick

Species

Human

Cat.No

ABC-SC0020T

Product Category

Stem Cells

Size/Quantity

1 vial

Cell Type

Induced Pluripotent Stem Cell

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Foreskin

Disease

Niemann Pick Type C

Storage

Liquid Nitrogen

Product Type

Human iPSCs

Application

  • HighQC™ Human iPSCs From Foreskin Fibroblasts (Morbus Niemann Pick Type C) serve as a physiologically relevant in vitro model for Niemann-Pick type C (NPC) disease mechanism investigation and drug screening applications. Researchers can utilize this platform for high-throughput compound screening to identify candidate compounds that restore cholesterol homeostasis, as well as for CRISPR-based gene editing studies to validate disease-associated molecular pathways. The model supports both mechanistic studies and preclinical evaluation of potential research applications.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring HighQC™ Human IPSC From Foreskin Fibroblast (Morbus Niemann Pick Type C)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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