HighQC™ Human IPSC From PBMC-Crohn’s Disease

Description

HighQC™ Human IPSC From PBMC-Crohn’s Disease is a disease-specific human induced pluripotent stem cell (iPSC) line derived from peripheral blood mononuclear cells (PBMCs) of a donor diagnosed with Crohn’s Disease, a chronic inflammatory bowel disorder (IBD). The reprogramming was performed using non-integrating episomal plasmid method. The resulting iPSCs exhibit adherent growth with a high nucleus-to-cytoplasm ratio. The Crohn’s Disease iPSCs preserve pluripotency for Crohn’s disease immune mechanism research. They retain the fundamental capacity for trilineage differentiation into cell types of all three germ layers (ectoderm, mesoderm, and endoderm). Core pluripotency SSEA-4 is expressed. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.