HighQC™ Human Osteosarcoma Cancer Stem Cell

Description

HighQC™ Human Osteosarcoma Cancer Stem Cells (HOCSCs) are a selected stem cell population derived from primary human osteosarcoma tumors. They exhibit typical small, round-to-oval morphology in suspension and can adhere when induced to differentiate. Importantly, osteosarcoma HOCSCs express well-established stemness markers, including CD133 and ALDH1, both associated with tumor aggressiveness, metastatic potential, and chemoresistance. These human bone cancer stem cells are originated directly from tumor specimens, preserving native oncogenic features. They demonstrate hallmark HOCSC traits, including clonogenic growth, sphere formation capacity, and resistance to standard chemotherapeutics such as doxorubicin and cisplatin. Their ability to self-renew, resist standard chemotherapies, and drive relapse highlights their central role in osteosarcoma biology. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.