HighQC™ Nephron Progenitor Cells

Description

HighQC™ Nephron Progenitor Cells are primary renal progenitor cells isolated from the cap mesenchyme of embryonic mouse kidney tissue (ICR outbred strain) at embryonic day 17.5 during the nephrogenic stage. These cells represent lineage-committed nephron progenitors (CITED1+) derived from non-diseased tissue. They exhibit limited proliferative capacity and can be maintained for up to 6 passages under optimized culture conditions (NPEM). Morphologically, they display typical progenitor-like characteristics and grow as adherent cells in vitro. These nephron cells characteristically express key nephron progenitor markers such as SIX2 and CITED1. Functionally, these cells possess the capacity to differentiate into multiple nephron epithelial lineages, including podocyte precursors and tubular epithelial cells under appropriate experimental conditions. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.