HighQC™ Porcine Bone Marrow Mesenchymal Stem Cell

Description

HighQC™ Porcine Bone Marrow Mesenchymal Stem Cells (pBM-MSCs) are primary mesenchymal stem cells isolated from the tibias and femurs bone marrow of healthy domestic pigs (Sus scrofa) via density-gradient centrifugation. These multipotent stromal cells exhibit a fibroblast-like, spindle-shaped morphology and possess high proliferative capacity. pBM-MSCs are typically cryopreserved at low passage numbers to maintain native charateristics. They express surface markers typical of MSCs, including CD29, CD44 and CD90, while lacking expression of the hematopoietic marker CD34 and CD45. Porcine MSCs can differentiate into osteogenic, chondrogenic, and adipogenic lineages under appropriate conditions. Calcium-binding proteins are upregulated during osteogenesis. Due to their physiological similarity to humans, porcine MSCs are widely used in preclinical models of tissue regeneration, immunomodulation, and xenotransplantation. They also support studies in cardiovascular, musculoskeletal, and inflammatory diseases.