HighQC™ Rat Inferior Mesenteric Plexus Neuronal Stem Cell

Description

HighQC™ Rat Inferior Mesenteric Plexus Neuronal Stem Cells (R-IMPSC) are derived from the autonomic ganglia of the inferior mesenteric plexus in postnatal rats and represent a population of enteric neural crest–derived progenitors. These cells exhibit neurosphere-forming ability and display small, bipolar or multipolar morphology consistent with early neuronal stem cells. They express canonical neural stem/progenitor markers including Nestin, and Sox10, and can differentiate into enteric neurons and glial cells under lineage-specific conditions. These neuronal stem cells demonstrate self-renewal capacity and are responsive to neurotrophic and morphogenic signals, such as brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF), enabling their use in modeling enteric neurogenesis and peripheral neuroplasticity. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from mycoplasma, fungi, yeast, and bacteria.