Horse Red Blood Cells

Description

Horse Red Blood Cells are purified erythrocyte preparations derived from horse whole blood through comprehensive washing procedures that remove the platelet-rich plasma, buffy coat layer, and leukocytes. These terminally differentiated cells lack nuclei and organelles, exhibit a characteristic biconcave disc morphology of mature mammalian erythrocytes, and contain high-purity hemoglobin optimized for gas exchange. Functionally, they transport oxygen bound to hemoglobin and facilitate CO2 removal. Studies link equine erythrocyte dysfunction to equine infectious anemia (EIA) and piroplasmosis. Unlike nucleated cells, these horse cells cannot proliferate or be passaged due to terminal differentiation. Cells are prepared in CPDA-1 anticoagulant and optionally leukocyte-reduced. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.