Human A2B5 Positive (A2B5+) Neural Cells

Description

Human A2B5 Positive (A2B5+) Neural Cells are isolated from whole brain tissue by rapid dissociation into single cells and purified via magnetic cell separation technology. Sourced from a single donor, these neural progenitor cells are capable of self-renewal and exhibit multipotent differentiation capacity, with the ability to generate neurons, astrocytes, and oligodendrocytes. Their dysfunction is implicated in demyelinating diseases like multiple sclerosis (MS) and various neurodegenerative disorders. Rigorous characterization confirms expression of the A2B5-reactive surface ganglioside epitope, a well-established marker of neural progenitor cells and a definitive marker of neural progenitor identity, along with frequent co-expression of the intermediate filament protein Nestin. As primary neural progenitors with sensitive biological properties, repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.