Human Acute Lymphoid Leukemia Bone Marrow Plasma (Relapsed/Refractory)

Description

Human Acute Lymphoid Leukemia Bone-Marrow Plasma is an acellular plasma fraction isolated from bone marrow of adult patients with relapsed or refractory acute lymphoblastic leukemia (ALL), predominantly of B-cell lineage with occasional T-ALL cases. This cell-free plasma contains leukemia-associated soluble mediators and extracellular vesicles, reflecting the leukemic bone-marrow microenvironment and supporting studies of diagnostic plasma markers in relapsed ALL, treatment efficacy through plasma biomarkers, and bone marrow plasma in relapsed leukemia. It is suitable for investigating disease progression, immune modulation, and therapy resistance. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.