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Transfected Stable Cell Lines

Human AKT1 (D323H_C310A) BAF3 Cell Line

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Species

Human

Cat.No

ABC-X0392C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human AKT1 (D323H_C310A) BAF3 Cell Line is a genetically engineered model derived from selected murine pro-B Ba/F3 parental cell line based on customers’ requirement. AKT1 (D323H_C310A) BAF3 overexpression cell line is generated by stable integration of exogenous human AKT1 gene carrying D323H and C310A mutations into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
AKT1 is a serine/threonine kinase that regulates cell survival, proliferation, and metabolism. Mutations D323H and C310A alter its catalytic or regulatory domains, modulating downstream PI3K/AKT pathway activation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The AKT1 (D323H_C310A) BAF3 Overexpression Cell Line supports functional analysis of AKT1 mutants and evaluation of AKT-targeted inhibitors in hematologic malignancy models.

Inquiring Human AKT1 (D323H_C310A) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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