Human Aortic Smooth Muscle Cells

Description

Human Aortic Smooth Muscle Cells (HASMCs) are mainly derived from the aortic media. Morphologically, HASMCs exhibit a spindle-shaped appearance with multiple processes. These cells express smooth muscle-specific markers, such as alpha-smooth muscle actin (α-SMA). Functionally, HASMCs regulate vascular tone through contraction and relaxation, thereby controlling blood flow and blood pressure. They also secrete extracellular matrix components to maintain the structure and function of the vascular wall. Under certain pathological conditions, HASMCs can exhibit changes in function and structure, including proliferation, migration, and phenotypic switching. These cells participate in vascular repair and remodeling. HASMCs serve as an essential in vitro model for investigating human smooth muscle cell signaling pathways and exploring the molecular mechanisms underlying HASMCs function. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.