Human Bladder Epithelial Cells are primary cells isolated from normal human bladder tissue, consisting of basal (cuboidal), intermediate (polygonal), and umbrella cells. They form a barrier regulating urine flow and protecting the bladder from toxins and infection. These cells express key biomarkers including CK5+, CK7+, CK8+, CK18+, P63+, E-cadherin+, ZO-1+, and α-smooth muscle Actin–, confirming their epithelial identity and tight junction integrity. They are non-tumorigenic and non-metastatic, tested negative for mycoplasma, bacteria, yeast, fungi, and viral infections (including HIV-1, HIV-2, HTLV I, HTLV II), ensuring purity. Cryopreserved in liquid nitrogen, they are suitable for studies related to bladder function, urological diseases, and cancer research.
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