+1 862-686-2696

  • Buy 1 Get 1 FREE for immortalized cells| limited time until end of June

  • Boost Your Research with FREE Freezing Medium

Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human BRAF (L597Q) NIH/3T3 Cell Line

  • For research use only

Cat No.

ABC-X0047C
Product Type

Overexpression Stable Cell Lines
Cell Type

Fibroblast
Species

Human
Host Cell

NIH/3T3
Source Organ

Embryo
Disease

Normal
Storage

Liquid Nitrogen

The BRAF (L597Q) NIH/3T3 cell line is a powerful tool for investigating tumor mechanisms, supporting targeted drug screening and resistance analysis.

Product Image
  • Human BRAF (L597Q) NIH/3T3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BRAF (L597Q) NIH/3T3 Cell Line

Description

Human BRAF (L597Q) NIH/3T3 Cell Line is a genetically engineered model derived from murine NIH/3T3 fibroblast cells based on customers’ requirement. BRAF (L597Q) NIH/3T3 mutant cell line is developed through stable lentiviral-mediated integration of the human BRAF gene containing the L597Q mutation.
Target
The L597Q mutation in BRAF lies adjacent to the activation segment of the kinase domain and leads to enhanced dimerization and increased downstream MEK/ERK pathway activation. It is recurrently observed in melanoma and other solid tumors, particularly in non-V600E mutant contexts. AcceGen specializes in generation of BRAF-mutant cell lines for oncogenic mechanism studies. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0047C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The BRAF (L597Q) NIH/3T3 Cell Line provides a potent tool to explore BRAF dimerization, mutation-specific signaling, and therapeutic vulnerabilities. It supports targeted drug screening, resistance analysis, and functional cancer genomics.

  • Online Inquiry
  • Product Reviews

Inquiring Human BRAF (L597Q) NIH/3T3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button