Human Cardiac Microvascular Endothelial Cells

Description

Human Cardiac Microvascular Endothelial Cells (HCMEC) are derived from human heart tissue and cryopreserved at early passage. HCMECs display a typical cobblestone-like morphology. These cells play a vital role in modulating both physiological and pathological functions of cardiomyocytes. HCMECs secrete cardiotropic factors such as nitric oxide, endothelin-1, prostaglandins, purines, and natriuretic peptides, all of which contribute to the regulation of myocardial function. These primary human heart microvascular endothelium cells serve as a critical in vitro model for studying cardiac microcirculation, endothelial signaling, and cardiovascular disease mechanisms. HCMECs express surface markers such as von Willebrand factor (vWF/Factor VIII) and CD31 (PECAM-1). The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.