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Human Chronic Kidney Disease Peripheral Blood Mononuclear Cells

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Clinical data may include: Medication (current and historical), Disease Severity, Creatine Clearance Value, GFR, standard blood chemistry results, BNP.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Chronic Kidney Disease Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4342
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Chronic Kidney Disease
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Chronic Kidney Disease Peripheral Blood Mononuclear Cells (PBMCs) are a type of mononuclear cell population derived from the peripheral blood of patients with chronic kidney disease (CKD), mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. CKD-PBMCs play a central role in immune regulation and inflammatory response. PBMCs in patients with chronic kidney disease usually show an abnormal activation state, manifested by increased secretion of proinflammatory cytokines (such as TNF-α, IL-6, IL-1β), as well as oxidative stress and mitochondrial dysfunction.

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Citation

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Application

  • Human Chronic Kidney Disease Peripheral Blood Mononuclear Cells can be used for investigating the pathogenesis, disease progression and potential treatment strategies of chronic kidney disease (CKD). These cells can also be used to analyze the secretion characteristics of pro-inflammatory cytokines (such as TNF-α, IL-6), changes in immune cell subsets (such as regulatory T cells, monocyte subtypes), and the regulatory effects of epigenetic modifications on immune function.

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