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Human CLIP1_LTK (D597N) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (D597N) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0049C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

The CLIP1 LTK (D597N) BAF3 Cell Line is engineered by expressing the CLIP1-LTK fusion with a D597N kinase domain mutation in BAF3 cells. Lentiviral transduction enables stable expression, confirmed by molecular assays.
Target
CLIP1-LTK fusions are reported in pediatric and adult lung cancers. The D597N mutation enhances LTK kinase activation, contributing to oncogenic signaling. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line supports studies of LTK-mediated oncogenesis, drug screening, and inhibitor resistance profiling in LTK fusion-positive tumors.

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