+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Primary Cells

Human Colonic Microvascular Endothelial Cells

  • For research use only

Cat No.

ABC-TC3571
Product Type

Intestinal Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Colonic
Disease

Normal
Storage

Liquid Nitrogen

Human Colonic Microvascular Endothelial Cells support vascular biology, inflammation research, and cell interaction studies within human colonic tissue.

Product Image
  • Human Colonic Microvascular Endothelial Cells
Get a Quote
Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Colonic Microvascular Endothelial Cells

Description

Human Colonic Microvascular Endothelial Cells (HCoMEC) are derived from human colon tissue and cryopreserved at early passage to ensure high viability and consistency. These cells express endothelial markers CD31 and von Willebrand Factor (vWF). These endothelial cells play a vital role in regulating blood flow, facilitating nutrient and gas exchange, and maintaining the integrity of the vascular barrier within the colon. In addition to their vascular functions, HCoMEC are actively involved in immune surveillance and have been implicated in the pathogenesis of inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. To preserve cellular function and quality, repeated freeze-thaw cycles should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

Human Colonic Microvascular Endothelial Cells, Colon MVECs Human, Human Colonic Microvascular ECs, HCoMVECs, Intestinal Microvascular Endothelial Cells
Species

Human
Cat.No

ABC-TC3571
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Colonic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Intestinal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Colonic Microvascular Endothelial Cells are a crucial model for studying intestinal vascular biology, mucosal immune regulation, and barrier integrity. They play an essential role in angiogenesis and inflammation during gastrointestinal disorders such as inflammatory bowel disease (IBD). Researchers use these cells to explore cytokine signaling, microbial interaction, and vascular permeability in the colonic microenvironment.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What are Human Colonic Microvascular Endothelial Cells?

    Human Colonic Microvascular Endothelial Cells are specialized cells that line the microvasculature (small blood vessels) within the colon. They play a critical role in regulating blood flow, nutrient exchange, and maintaining the integrity of the vascular barrier in the colon.

  • What functions do Human Colonic Microvascular Endothelial Cells perform in the colon?

    Human Colonic Microvascular Endothelial Cells are involved in regulating blood flow and permeability, facilitating nutrient and gas exchange, and maintaining the vascular barrier to prevent the leakage of blood components into the surrounding tissue. They also play a role in immune response and inflammation within the colon.

  • What are Human Colonic Microvascular Endothelial Cells used for in research?

    Human Colonic Microvascular Endothelial Cells are used in research to study colonic vascular physiology, inflammatory bowel diseases (such as Crohn’s disease and ulcerative colitis), colorectal cancer, and the effects of various drugs on the colonic vasculature. They are also utilized in investigations of angiogenesis and vascular permeability in the colon.

  • How are Human Colonic Microvascular Endothelial Cells isolated from colonic tissue?

    Human Colonic Microvascular Endothelial Cells are isolated from colonic tissue through a combination of enzymatic digestion and mechanical dissociation. The tissue is typically minced and treated with enzymes to break down the extracellular matrix, followed by mechanical agitation to release the endothelial cells. The cells are then purified using specific markers or selection techniques to ensure a pure population of Human Colonic Microvascular Endothelial Cells.

  • Online Inquiry
  • Product Reviews

Inquiring Human Colonic Microvascular Endothelial Cells

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button