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Primary Cells

Human Corneal Epithelial Cells

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The cornea is a unique tissue for two reasons: the transparency function and the synthesis of most of its proteins due to the cornea being an avascular tissue. The cornea consists of three distinct cell layers, the outer epithelium, the inner endothelium and the central stroma (the keratocytes). The corneal epithelium plays a role in […]
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Home | Primary Cells | Human Primary Cells | Nervous System Primary Cells | Human Corneal Epithelial Cells
Product Code

HCEpiC
Species

Human
Cat.No

ABC-TC3577
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Corneal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Ocular Cells
Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Description

Human Corneal Epithelial Cells originate from the outermost layer of the cornea, the stratified squamous epithelium, which can be divided into three layers: basal cells, wing cells, and surface squamous cells . They express cytokeratin 3 and cytokeratin 12, markers specific to differentiated corneal epithelial cells, detectable by immunocytochemistry.Their morphology shows typical polygonal squamous epithelial-like features. These cells can form a mechanical barrier to resist the invasion of pathogens, secrete antimicrobial peptides (such as defensins) and cytokines to participate in innate immunity.Dysfunction of these cells is associated with diseases such as dry eye syndrome, infectious keratitis, and corneal epithelial defects. In addition, they can maintain corneal transparency through tight junctions.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Corneal Epithelial Cells can be used to study corneal epithelial barrier function, wound healing mechanisms, and innate immune responses, such as studying the interaction between pathogens and the cornea through in vitro models. These cells can also be used to evaluate the permeability, toxicity, and repair effects of ocular drugs (such as antibiotics and anti-inflammatory drugs).

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