For research use only
| Cat No. | ABC-X0318C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Lymphocytes |
| Species | Human |
| Host Cell | BAF3 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human EGFR (C595S) BAF3 Cell Line supports investigation of EGFR variant-induced signaling alterations and their effects on cancer progression and therapy.
Human EGFR (C595S) BAF3 Overexpression Cell Line is generated by lentiviral transduction of Ba/F3 cells with a construct encoding human EGFR harboring the C595S mutation. Clones are maintained at <P20 and validated at the transcriptional level by qRT-PCR. Target EGFR is a receptor tyrosine kinase whose mutations drive tumorigenesis in non-small cell lung cancer and glioblastoma. The C595S variant affects the extracellular domain and may influence ligand binding or dimerization properties. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.
| Species | Human |
| Cat.No | ABC-X0318C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This cell model supports the study of EGFR (C595S) biology and pharmacologic responses, aiding the development of next-generation EGFR-targeted therapies and resistance analysis.