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| Species | Human |
| Cat.No | ABC-X0318C |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
Human EGFR (C595S) BAF3 Overexpression Cell Line is generated by lentiviral transduction of Ba/F3 cells with a construct encoding human EGFR harboring the C595S mutation. Clones are maintained at <P20 and validated at the transcriptional level by qRT-PCR. Target EGFR is a receptor tyrosine kinase whose mutations drive tumorigenesis in non-small cell lung cancer and glioblastoma. The C595S variant affects the extracellular domain and may influence ligand binding or dimerization properties. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.
For research use only