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Transfected Stable Cell Lines

Human EGFR (R108K) BAF3 Cell Line

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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-X0050C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocyte

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human EGFR (R108K) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. EGFR (R108K) BAF3 mutant cell line is generated by stable integration of exogenous human EGFR gene harboring the R108K mutation into Ba/F3 host cells using our optimized lentiviral transduction system.
Target
EGFR is a transmembrane tyrosine kinase receptor regulating cell growth, survival, and differentiation through PI3K/AKT and MAPK signaling pathways. The R108K mutation, located in the extracellular domain, has been implicated in ligand-independent receptor dimerization and activation, contributing to oncogenesis. AcceGen provides customized EGFR-mutant models to support research into drug resistance, structure-function studies, and targeted therapy development. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The EGFR (R108K) BAF3 Cell Line serves as a robust tool for functional analysis of EGFR activation, ligand-independent signaling, and therapeutic inhibition. It facilitates studies on mutant EGFR-driven tumorigenesis and preclinical testing of EGFR-targeted agents.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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