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Primary Cells

Human Epidermal Melanocytes-dark

  • For research use only

Cat No.

ABC-TC3608
Product Type

Melanocyte
Cell Type

Melanocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Storage

Liquid Nitrogen

HEM-d from AcceGen Research Laboratories are isolated from neonate human epidermis.

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  • Human Epidermal Melanocytes-dark
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Home | Primary Cells | Human Primary Cells | Others | Human Epidermal Melanocytes-dark

Description

Human Epidermal Melanocytes-dark (HEM-d) are spindle-shaped, adherent cells derived from normal human skin obtained from healthy donors. As neural crest–origin pigment cells, they reside in the basal layer of the epidermis and transfer melanin-containing melanosomes to keratinocytes via dendritic projections, contributing to cutaneous pigmentation and UV protection. HEM-d express characteristic markers including NGF receptor (p75), fibronectin, and S100β. These cells are cryopreserved at early passage. Their defined morphology makes HEM-d a reliable model in pigment biology and dermatological studies. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Dark Pigmented Epidermal Melanocytes, Dark Skin Melanocytes Human, NHEM-Dark, Human Epidermal Melanocytes Dark Type, Pigmented Melanocytes Dark
Species

Human
Cat.No

ABC-TC3608
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Melanocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Melanocyte
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HEM-d cells are widely used in research on melanin biosynthesis, melanocyte-keratinocyte interactions, and pigment regulation in 2D and 3D skin equivalents. Their expression of CITED1 enables transcriptional studies on melanogenesis and melanoma progression. These cells serve as models for pigmentary disorders such as vitiligo and Waardenburg syndrome, and support screening of whitening agents, antioxidants, and UV-protective compounds in dermatological studies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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