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Primary Cells

Human Epidermal Melanocytes-light

  • For research use only

Cat No.

ABC-TC3610
Product Type

Melanocyte
Cell Type

Melanocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Storage

Liquid Nitrogen

HEM from AcceGen Research Laboratories are isolated from neonate human epidermis.

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  • Human Epidermal Melanocytes-light
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Home | Primary Cells | Human Primary Cells | Others | Human Epidermal Melanocytes-light

Description

Human Epidermal Melanocytes-light (HEM-light) are adherent, spindle-shaped pigment cells derived from normal human neonatal skin obtained from healthy donors. As neural crest–derived cells, they reside within the basal epidermal layer, synthesizing melanin in melanosomes and extending dendritic processes to transfer pigments to keratinocytes, supporting skin pigmentation and UV defense. These cells express characteristic melanocyte markers including NGF-receptor (p75), fibronectin, S100β, MITF, TYRP1, and gp100/HMB-45. Cryopreserved at early passage, their defined morphology and light-pigmented phenotype make them an excellent model for pigment biology and photoprotection studies. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Light Pigmented Epidermal Melanocytes, Light Skin Melanocytes Human, NHEM-Light, Human Epidermal Melanocytes Light Type, Pigmented Melanocytes Light
Species

Human
Cat.No

ABC-TC3610
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Melanocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Melanocyte
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HEM-light cells are ideal for studies of lower baseline melanogenesis, dendritic pigment transfer, and melanosome packaging in lightly pigmented skin models. They support mechanistic research into UV response, melanin-type balance (eumelanin vs pheomelanin), and pigmentary disorder therapeutics, such as vitiligo and hypopigmentation. Their well-characterized marker profile and human origin also make them suitable for preclinical screening of depigmenting agents, antioxidants, and cosmetic actives within 2D/3D skin equivalents.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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