Human Melanocytes, Adult

Description

Human Melanocytes, Adult are primary melanocytes isolated from normal human skin. Following primary culture, these cells are cryopreserved. The cells exhibit characteristic stellate or multipolar dendritic morphology and perform the essential biological function of melanin synthesis and distribution, which protects skin from UV radiation and determines skin pigmentation, making them a reliable in vitro model for adult skin pigmentation studies. Dysfunction or loss of melanocytes is implicated in pigmentary disorders such as vitiligo, melasma, and albinism, as well as in the development of malignant melanoma. As primary cells, they possess limited proliferative capacity and require specialized media for optimal growth. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.