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Primary Cells

Human Epidermal Melanocytes, Fetal

  • For research use only

Cat No.

ABC-TC3609
Product Type

Melanocyte
Cell Type

Melanocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Storage

Liquid Nitrogen

Human Epidermal Melanocytes, Fetal, support pigmentation biology, melanocyte function studies, and skin disorder research in developmental dermatology.

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  • Human Epidermal Melanocytes, Fetal
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Home | Primary Cells | Human Primary Cells | Others | Human Epidermal Melanocytes, Fetal

Description

Human Epidermal Melanocytes-fetal (HEM-fetal) are dendritic pigment cells derived from normal human fetal skin obtained from healthy donors, exhibiting adherent growth and spindle-shaped morphology. As neural crest–origin melanocytes, they migrate during embryogenesis to the basal epidermal layer and hair follicles, synthesizing melanin in melanosomes and extending dendrites to transfer pigment to keratinocytes, contributing to skin pigmentation, UV protection, and cutaneous homeostasis. HEM-fetal express melanocyte-specific markers such as KIT, TYRP, and gp100 (HMB-45), which are critical for melanogenesis and cell maturation. Their embryonic-stage origin and stable phenotype make HEM-fetal ideal for developmental pigment research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Fetal Epidermal Melanocytes, Prenatal Melanocytes Human, Fetal Skin Melanocytes, NHEM-Fetal, Human Cutaneous Melanocytes Fetal
Species

Human
Cat.No

ABC-TC3609
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Melanocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Melanocyte
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HEM-fetal cells enable investigation into embryonic melanocyte migration, differentiation, and melanin-related signaling pathways in fetal skin development models. They support co-culture with fetal keratinocytes to examine melanocyte–epidermal unit formation and regulation of melanocyte numbers by keratinocyte-derived factors. Additionally, HEM-fetal serve as a valuable model for developmental pigmentary disease research, early-stage drug screening, and evaluating pigmentation modulators or melanogenic inhibitors in preclinical studies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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