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Transfected Stable Cell Lines

Human ERBB2 (V956R) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0286C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human ERBB2 (V956R) BAF3 Cell Line allows investigation of HER2 mutation-driven oncogenesis and targeted drug sensitivity in cancer cells.

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  • Human ERBB2 (V956R) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (V956R) BAF3 Cell Line

Description

Human ERBB2 (V956R) BAF3 Cell Line is a genetically engineered model derived from murine Ba/F3 cells with stable integration of human ERBB2 gene carrying the V956R activating mutation. The cell line was generated using lentiviral transduction and expanded under low passage conditions (<P20). Expression is confirmed by qRT-PCR. Target ERBB2 (HER2) is a member of the ERBB receptor tyrosine kinase family involved in cell growth and differentiation. The V956R mutation occurs within the kinase domain, enhancing dimerization and downstream signaling. It is implicated in drug resistance in HER2-positive cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0286C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model is ideal for evaluating ERBB2 mutation-driven signaling, HER2-targeted therapy response, and resistance mechanisms in hematologic and solid tumor settings.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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