+1 862-686-2696

  • Buy 1 Get 1 FREE for immortalized cells| limited time until end of June

  • Boost Your Research with FREE Freezing Medium

Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human FGFR2 (C491S) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0037C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocyte
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The FGFR2 (C491S) BAF3 cell line is a genetically engineered model suitable for studying FGFR2-mediated tumor signaling pathways and drug screening.

Product Image
  • Human FGFR2 (C491S) BAF3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2 (C491S) BAF3 Cell Line

Description

Human FGFR2 (C491S) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. FGFR2 (C491S) BAF3 mutant cell line is generated by stable integration of exogenous human FGFR2 gene harboring the C491S mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
FGFR2 is a transmembrane receptor tyrosine kinase that regulates cell proliferation, migration, and differentiation through FGF signaling. The C491S mutation disrupts a conserved cysteine residue in the extracellular domain, promoting ligand-independent dimerization and constitutive activation. This mutation is associated with tumorigenesis in endometrial and gastric cancers. AcceGen provides customized cell models featuring oncogenic mutations for pathway and drug discovery research. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0037C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The FGFR2 (C491S) BAF3 Cell Line is an ideal model to explore FGFR2-mediated oncogenic signaling, evaluate the efficacy of FGFR inhibitors, and study downstream resistance mechanisms. It supports high-throughput drug screening and precision therapy development for FGFR-driven malignancies.

  • Online Inquiry
  • Product Reviews

Inquiring Human FGFR2 (C491S) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button