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Transfected Stable Cell Lines

Human FGFR2_BICC1 (K714R) NIH/3T3 Cell Line

  • For research use only

Cat No.

ABC-X0378C
Product Type

Overexpression Stable Cell Lines
Cell Type

Fibroblast
Species

Human
Host Cell

NIH/3T3
Source Organ

Embryo
Disease

Normal
Storage

Liquid Nitrogen

Human FGFR2_BICC1 (K714R) NIH/3T3 Cell Line, FGFR2, BICC1, Overexpression Stable Cell Lines, Transfected Stable Cell Lines

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  • Human FGFR2_BICC1 (K714R) NIH/3T3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2_BICC1 (K714R) NIH/3T3 Cell Line

Description

Human FGFR2_BICC1 (K714R) NIH/3T3 Cell Line is a genetically engineered model derived from selected murine embryonic fibroblast NIH/3T3 parental cell line based on customers’ requirement. FGFR2_BICC1 (K714R) NIH/3T3 overexpression cell line is generated by stable integration of exogenous human FGFR2-BICC1 fusion gene with the K714R point mutation into NIH/3T3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
FGFR2-BICC1 is an oncogenic gene fusion frequently observed in intrahepatic cholangiocarcinoma. The K714R mutation enhances FGFR kinase activity and oncogenicity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0378C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The FGFR2_BICC1 (K714R) NIH/3T3 Overexpression Cell Line provides a robust model to investigate FGFR fusion–driven tumorigenesis and to assess FGFR-targeted therapies in preclinical settings.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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