+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human FGFR3 (V555M) NIH/3T3 Cell Line

  • BSL

    1

  • 16
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR3 (V555M) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0023C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human FGFR3 (V555M) NIH/3T3 Cell Line is a genetically engineered model derived from selected murine NIH/3T3 parental cell line based on customers’ requirement. FGFR3 (V555M) NIH/3T3 mutant cell line is generated by stable integration of exogenous human FGFR3 gene harboring the V555M point mutation into NIH/3T3 host cells using our optimized transduction of lentiviral vectors.
Target
FGFR3 encodes fibroblast growth factor receptor 3, a transmembrane tyrosine kinase involved in cell differentiation, proliferation, and survival. The V555M mutation occurs in the kinase domain and has been reported as an activating mutation associated with oncogenic transformation. FGFR3 alterations are implicated in multiple malignancies including bladder cancer, multiple myeloma, and cervical cancer. AcceGen offers generation of stable overexpression and mutation-specific cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only

  • The FGFR3 (V555M) NIH/3T3 Cell Line serves as a powerful tool to investigate FGFR3-mediated signaling and oncogenesis. This model enables mechanistic studies of constitutive kinase activation, MAPK/ERK pathway upregulation, and response to FGFR-targeted inhibitors. It is utilized for preclinical drug screening and validation of precision oncology therapeutics.

  • Online Inquiry
  • Product Reviews

Inquiring Human FGFR3 (V555M) NIH/3T3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button