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Transfected Stable Cell Lines

Human FGFR3_TACC3 (L608V) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR3_TACC3 (L608V) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0044C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

The FGFR3 TACC3 (L608V) BAF3 Cell Line expresses the FGFR3-TACC3 fusion gene carrying the L608V activating mutation in BAF3 cells. The mutation enhances kinase function and contributes to therapeutic resistance. Cells are stably transduced and validated for gene expression.
Target
FGFR3-TACC3 fusions drive glioblastoma and bladder cancer progression. The L608V mutation boosts kinase activation and modulates therapeutic response. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Used for functional studies of FGFR3-TACC3 signaling, resistance profiling, and development of FGFR-targeted therapeutics.

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