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Transfected Stable Cell Lines

Human FGFR3_TACC3 (L608V) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0044C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

This model expresses FGFR3-TACC3 (L608V) fusion for exploring the altered signaling, oncogenic transformation, and testing anti-FGFR therapies.

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  • Human FGFR3_TACC3 (L608V) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR3_TACC3 (L608V) BAF3 Cell Line

Description

The FGFR3 TACC3 (L608V) BAF3 Cell Line expresses the FGFR3-TACC3 fusion gene carrying the L608V activating mutation in BAF3 cells. The mutation enhances kinase function and contributes to therapeutic resistance. Cells are stably transduced and validated for gene expression.
Target
FGFR3-TACC3 fusions drive glioblastoma and bladder cancer progression. The L608V mutation boosts kinase activation and modulates therapeutic response. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0044C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Used for functional studies of FGFR3-TACC3 signaling, resistance profiling, and development of FGFR-targeted therapeutics.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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