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Primary Cells

Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells

  • For research use only

Cat No.

ABC-TC4364
Product Type

Diseased Human Peripheral Blood Mononuclear Cells
Cell Type

Mononuclear Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Idiopathic Pulmonary Fibrosis
Storage

Liquid Nitrogen

Explore Human Idiopathic Pulmonary Fibrosis PBMCs for studying immune dysregulation, fibrosis progression, and chronic lung disease biomarker discovery.

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  • Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells

Description

Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells are immune cells isolated from the peripheral blood of Idiopathic Pulmonary Fibrosis (IPF) patients, primarily comprising lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play key roles in immune regulation, inflammation, and fibrosis progression in IPF. Monocytes differentiate into profibrotic macrophages, secreting TGF-β and PDGF to activate fibroblasts, while aberrant T-cell responses exacerbate collagen deposition. IPF-PBMCs are linked to chronic inflammation, aberrant wound healing, and progressive lung scarring, with altered cytokine profiles (elevated IL-4, IL-13, IL-17A) contributing to disease pathogenesis.

Species

Human
Cat.No

ABC-TC4364
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Idiopathic Pulmonary Fibrosis
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Application

  • Human Idiopathic Pulmonary Fibrosis (IPF) Peripheral Blood Mononuclear Cells can be used to study the immune pathogenesis of IPF. These cells can also be used to evaluate the immunomodulatory effects of existing anti-fibrotic drugs (such as nintedanib and pirfenidone), and to screen new therapeutic drugs targeting specific inflammatory pathways.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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