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Human KIF5B_RET (L865V) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human KIF5B_RET (L865V) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0351C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human KIF5B_RET (L865V) BAF3 Overexpression Cell Line is a genetically engineered model derived from murine BAF3 pro-B cells based on customers’ requirement. The cell line is constructed via stable integration of human KIF5B-RET fusion carrying a L865V mutation using optimized lentiviral transduction. The overexpressing clone is verified by qRT-PCR and maintained at low passage numbers (

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Designed for modeling the L865V point mutation in the KIF5B-RET fusion protein, this cell line facilitates analysis of mutation-driven signaling changes, oncogenic activity, and drug resistance. It provides a robust system for evaluating RET inhibitor efficacy, mapping phosphorylation dynamics, and testing mutation-specific responses to kinase-targeted compounds in controlled hematopoietic cell settings.

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