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Primary Cells

Human Mammary Fibroblasts

  • For research use only

Cat No.

ABC-TC3694
Product Type

Mammary Cells
Cell Type

Fibroblast
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mammary
Disease

Normal
Storage

Liquid Nitrogen

Human Mammary Fibroblasts from AcceGen Research Laboratories are isolated from human mammary tissue.

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  • Human Mammary Fibroblasts
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Home | Primary Cells | Human Primary Cells | Endocrine System Primary Cells | Human Mammary Fibroblasts

Description

Human Mammary Fibroblasts are primary cells isolated from healthy adult breast stromal tissue, obtained with informed donor consent. These fibroblasts exhibit a classic mesenchymal spindle-shaped morphology and are cryopreserved at an early passage to preserve their native state. In culture, they express fibroblast marker vimentin (VIM). Normal mammary fibroblasts play a crucial role in branching morphogenesis during gland development, secrete extracellular matrix components like collagen and fibronectin, and regulate epithelial behavior through paracrine signaling. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Mammary Fibroblasts, Breast Fibroblasts Human, HMFs, Mammary Stromal Fibroblasts, Human Breast Connective Tissue Cells
Species

Human
Cat.No

ABC-TC3694
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mammary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mammary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Mammary Fibroblasts are ideal for in vitro studies exploring stromal–epithelial interactions, extracellular matrix remodeling, and stromal contributions to breast development and disease. They are widely used in 3D co-culture models to examine normal branching morphogenesis and tumor-stroma crosstalk, as well as to investigate how fibroblast-derived VEGF drives angiogenesis under hypoxic conditions in breast tissue. These cells also serve as critical controls in cancer-associated fibroblast (CAF) studies, helping to decipher how stromal reprogramming contributes to tumor progression, invasion, fibrosis, and therapy resistance.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
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To support a consistent result
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