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Primary Cells

Human Mammary Microvascular Endothelial Cells

  • For research use only

Cat No.

ABC-TC3696
Product Type

Mammary Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mammary
Disease

Normal
Storage

Liquid Nitrogen

Human Mammary Microvascular Endothelial Cells support tumor angiogenesis, breast microvascular biology, and endothelial barrier function research.

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  • Human Mammary Microvascular Endothelial Cells
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Home | Primary Cells | Human Primary Cells | Endocrine System Primary Cells | Human Mammary Microvascular Endothelial Cells

Description

Human Mammary Microvascular Endothelial Cells (HMMECs) are isolated from the microvasculature of normal human breast tissue, typically from reduction mammoplasty specimens. These primary human cells form a confluent monolayer in culture and exhibit a classic cobblestone morphology. HMMECs express key endothelial marker CD31 (PECAM-1), reflecting their microendothelial lineage. Functionally, they retain critical capabilities such as acetylated LDL (Ac-LDL) uptake and TNF-α–induced E-selectin (SELE) upregulation in breast environment. The cells are cryopreserved at an early passage to maintain genome stability. Thawed cells consistently show high viability. As primary cells, HMMECs have a finite replication capacity and are not suitable for long-term expansion. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Mammary Microvascular Endothelial Cells, Breast MVECs Human, HMMVECs, Mammary Microvascular ECs, Human Breast Endothelial Cells
Species

Human
Cat.No

ABC-TC3696
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mammary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mammary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HMMECs provide a physiologically relevant in vitro model for studying breast microvascular biology. They are ideal for investigating endothelial barrier function, angiogenesis, and inflammatory responses. Researchers can use them to investigate mechanotransduction (e.g., matrix stiffness effects on migration and proliferation), tumor-endothelial cell interactions, cancer-associated vascular remodeling, and high-throughput screening of anti-angiogenic or endothelial-targeted therapies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
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