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Human Mesenchymal Stem Cells from Umbilical Cord Arteries

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hUCAs-MSCs are human mesenchymal stem cells (hMSC) specifically taken from umbilical cord artery tissues. Differentiation studies have shown variation between the cord regions, meaning that for some studies MSCs from specific cord regions may be of interest. The harvesting procedure is non-invasive, with umbilical cords obtained from women with healthy pregnancies during caesarean deliveries at […]
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Product Code

hUCAs-MSCs

Species

Human

Cat.No

ABC-H0034Y

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Mesenchymal Stem Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Umbilical Cord Arteries

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Mesenchymal Stem Cells

Description

Human Mesenchymal Stem Cells from Umbilical Cord ArteriesHuman Mesenchymal Stem Cells from Umbilical Cord Arteries (hUCAs-MSCs) are derived from the arteries of human umbilical cords from healthy donors. These cells possess the remarkable ability to self-renew while maintaining their multipotency, making them suitable for various applications in research and therapy. They exhibit a spindle fibroblast-like morphology and express markers like CD29, CD44, CD95, CD105, and HLA-I, with a normal karyotype. hUCAs-MSCs can differentiate into osteogenic and adipogenic cells in vitro. Harvested non-invasively and cryopreserved to maintain functionality, these cells undergo rigorous quality control to ensure. Although no mutations are noted, long-term culturing may lead to genomic instability. In preclinical studies, hUCAs-MSCs have shown no tumorigenicity even at high doses in animal models. Suitable for drug testing, regenerative medicine, and disease research, hUCAs-MSCs are a valuable tool for studying various pathological conditions and validating therapies.

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Citation

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Application

  • Human Mesenchymal Stem Cells from Umbilical Cord Arteries (UC-MSCs) have a wide range of applications. In drug testing, they serve as a valuable platform for assessing the safety and efficacy of therapeutic compounds. In the research of regenerative medicine, UC-MSCs hold promise for tissue repair and regeneration due to their self-renewal capacity and multi-lineage differentiation potential. Moreover, these cells are instrumental in disease research,used to study various pathological conditions and uncover new insights. Additionally, UC-MSCs can be utilized in diseased animal models to validate their therapeutic potential, enabling researchers to assess the effectiveness of therapies before advancing to clinical trials.

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