Human Mesothelial Cells, Adult, Single Donor

Description

Human Mesothelial Cells, Adult, Single Donor are isolated from omental tissue biopsies of a single clinically screened adult donor, providing a genetically consistent primary cell model. These cells exhibit characteristic cobblestone epithelial morphology and grow as adherent monolayers. The cells maintain critical physiological properties, including essential barrier functions supported by hyaluronan secretion and providing friction-reducing surfaces for organs. Cryopreserved at early passage to preserve genetic integrity, they enable precise modeling of peritoneal dialysis complications and post-surgical adhesion formation. These mesothelial cells express mesothelial markers calretinin and podoplanin (D2-40). As primary cells, they possess limited proliferative capacity and cannot undergo long-term expansion. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.