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Human Monocyte-Derived Dendritic Cells

Product Name

Human Monocyte-Derived Dendritic Cells

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Cat.No

ABC-TC3708

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Dendritic cells (DCs) are a class of bone-marrow derived leukocytes with phagocytic and antigen presentation capability. They are considered as the bridge between innate and adaptive immune system where they capture, transport, process and present antigenic products to T cells in the lymph node. Dendritic cells can not only secret cytokines and growth factors to induce immune responses, but also induce tolerance to self-antigens. Monocyte-derived dendritic cells (mo-DCs) DC, which arise from CD34+ hematopoietic precursor, are a unique subpopulation of DC found at site of inflammatory. In vitro derived DCs from monocytes possess the characteristics of immature DCs and have been extensively used in immunological research, especially in cancer therapy.

Why choose Human Monocyte-derived dendritic cells from AcceGen?

AcceGen human monocyte-derived dendritic cells are derived from purified monocytes that cultured with IL-4 and GM-CSF. After 7 days, cells are harvested and cryopreserved immediately to ensure highest viability. Each vial contains more than 1.5×10^6 cells. Human monocyte-derived dendritic cells are characterized with the cell surface marker CD11c and HLA-DR. All cell lots are tested negative for HIV-1, HBV, HCV and other pathogens. Cells should be preserved in Liquid Nitrogen upon receive and should be used immediately once thawed.

Disease

Normal

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Human monocyte derived dendritic cells are quality guaranteed cell source with great functional plasticity that can be used for dendritic cell downstream research and translational research. They can be used for dendritic cell characterization, expression profiling and pathway characterization.

Owning to their superior capacity in mediating T cells, monocyte-derived dendritic cells have been increasingly used as vectors or adjuvants in cancer vaccine development and to promote immune tolerance to allograft.

Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-tested for accurate results

– Expert teams to provide timely support and assist best experimental outcomes

Growth Conditions

37 ℃, 5% CO2

Cell Type

DC Cell

Growth Mode

Suspension

Product Type

Immune Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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