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Transfected Stable Cell Lines

Human NRAS (G12D) NIH/3T3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (G12D) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0310C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human NRAS (G12D) NIH/3T3 Cell Line is a genetically engineered fibroblast cell line stably expressing the G12D mutant of human NRAS. It is commonly used in oncogenic transformation studies and drug discovery.
Target
NRAS G12D is a gain-of-function mutation that disrupts GTPase activity, leading to constitutive pathway activation. It is frequently found in melanoma and acute myeloid leukemia.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Used for Ras signaling studies, this model helps evaluate the efficacy of Ras/MAPK pathway inhibitors and dissect mutation-specific responses.

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