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Transfected Stable Cell Lines

Human NRAS (G12V) NIH/3T3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (G12V) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0312C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human NRAS (G12V) NIH/3T3 Cell Line features stable expression of the G12V mutant NRAS gene. NIH/3T3 cells provide a sensitive background for oncogene-driven transformation assays.
Target
G12V is a hotspot mutation in NRAS, conferring constitutive activation and resistance to negative regulatory mechanisms. It is prevalent in melanoma and hematologic cancers.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model supports detailed studies on NRAS G12V oncogenic mechanisms, therapeutic target validation, and resistance development to RAS pathway inhibitors.

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