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Transfected Stable Cell Lines

Human NRAS (G12V) NIH/3T3 Cell Line

  • For research use only

Cat No.

ABC-X0312C
Product Type

Overexpression Stable Cell Lines
Cell Type

Fibroblast
Species

Human
Host Cell

NIH/3T3
Source Organ

Embryo
Disease

Normal
Storage

Liquid Nitrogen

Human NRAS (G12V) NIH/3T3 Cell Line allows functional studies of NRAS oncogenic activation and its role in tumor cell proliferation and drug response.

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  • Human NRAS (G12V) NIH/3T3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (G12V) NIH/3T3 Cell Line

Description

Human NRAS (G12V) NIH/3T3 Cell Line features stable expression of the G12V mutant NRAS gene. NIH/3T3 cells provide a sensitive background for oncogene-driven transformation assays.
Target
G12V is a hotspot mutation in NRAS, conferring constitutive activation and resistance to negative regulatory mechanisms. It is prevalent in melanoma and hematologic cancers.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0312C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model supports detailed studies on NRAS G12V oncogenic mechanisms, therapeutic target validation, and resistance development to RAS pathway inhibitors.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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