+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Primary Cells

Human Oral Keratinocytes

  • For research use only

Cat No.

ABC-TC3733
Product Type

Oral Cells
Cell Type

Keratinocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Oral
Disease

Normal
Storage

Liquid Nitrogen

Human Oral Keratinocytes (HOKs) are primary oral epithelial cells that form a barrier,produce cytokines,express keratins,have limited passages in culture.

Product Image
  • Human Oral Keratinocytes
Get a Quote
Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Oral Keratinocytes

Description

Human Oral Keratinocytes (HOKs) are primary epithelial cells isolated from the oral mucosa of healthy donors. These cells exhibit an adherent growth and display epithelial-like morphology, typically appearing as irregularly shaped polygonal or flattened cells. As the predominant cell type in the oral epithelium, HOKs serve as the primary physical and immunological barrier against microbial invasion and chemical insults. Functionally, they participate in inflammatory responses by producing cytokines, which are crucial for maintaining mucosal immunity. HOKs express high levels of keratins (K5/K14 and K6/K16, K17) and E-cadherin. They demonstrate limited proliferative capacity in culture and are highly sensitive to freeze-thaw cycles, therefore repeated cryopreservation should be avoided.

Product Code

HOK
Species

Human
Cat.No

ABC-TC3733
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Keratinocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Oral
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Oral Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Oral Keratinocytes (HOKs) provide a versatile, serum-free culture model for research in oral mucosal physiology and disease mechanisms. They are particularly valuable for studying epithelial barrier integrity, wound healing, and host-pathogen interactions. Their innate cytokine production makes them valuable for investigating inflammatory responses to microbial biofilms or chemical irritants in conditions like periodontitis or oral mucositis. In tissue engineering, these cells serve as components for reconstructing stratified epithelium in 3D culture systems that mimic oral mucosa for transplantation studies. Cultured primary HOKs retain donor-specific characteristics, enabling personalized studies on genetic predispositions to oral disorders.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What is the origin site of the Human Oral Keratinocytes? Are they from the gingiva, buccal site, or another oral area?

    For Human Oral Keratinocytes, the cells are typically isolated from the buccal mucosa of the mouth. If the customer has specific requirements, such as cells from the gingiva or other areas, they can mention this when placing the order, and we can provide those as well.

  • What is the recommended number of passages for culturing these cells after receipt?

    Human oral keratinocytes are recommended for approximately 3 passages to maintain consistent morphology and functional properties.

  • Is this cell line suitable for cytotoxicity testing?

    Yes, these cells are suitable for in vitro cytotoxicity assays.

  • Online Inquiry
  • Product Reviews

Inquiring Human Oral Keratinocytes

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button