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Primary Cells

Human Pancreatic Alpha Cells

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Species

Human

Cat.No

ABC-TC146W

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Pancreatic Alpha Cell

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Pancreatic islets

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Pancreatic Cells

Description

Human Pancreatic Alpha Cells are primary cells isolated from human pancreatic islets, responsible for the secretion of glucagon, a hormone that raises blood glucose levels during hypoglycemia. These cells are characterized by the expression of glucagon, a key marker for alpha cells. In vitro, they exhibit responsiveness to glucose and other stimuli, making them valuable for studying glucose homeostasis and endocrine pancreas function. Human Pancreatic Alpha Cells also serve as a model for investigating alpha cell dysfunction in diabetes and exploring potential therapeutic strategies for diabetes management.

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Application

  • For research use only.

  • Human Pancreatic Alpha Cells are used to study glucagon secretion mechanisms, glucose sensing, and interactions between islet cells. They are employed in diabetes research, particularly in understanding alpha cell dysfunction in type 1 and type 2 diabetes. Additionally, these cells provide a model for drug screening and regenerative medicine studies, with an emphasis on developing therapies for beta cell restoration through alpha cell transdifferentiation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
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