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Primary Cells

Human Pancreatic Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the Pancreas, Carcinoma of the Pancreas.
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Species

Human

Cat.No

ABC-TC4331

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Pancreatic Cancer

Storage

Liquid Nitrogen

Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Pancreatic Cancer Peripheral Blood Mononuclear Cells are primarily derived from the peripheral blood of pancreatic cancer patients. They are a mixed cell population separated from the blood by density gradient centrifugation, including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are generally round or oval. In the tumor microenvironment, these cells can participate in anti-tumor or tumor-promoting processes by secreting cytokines (such as IL-6, TNF-α) and mediating immune responses, among which regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSCs) may facilllitate immune escape.

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Citation

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Application

  • Human Pancreatic Cancer Peripheral Blood Mononuclear Cells can be used to study the tumor immune microenvironment, such as evaluating the activity and immunosuppressive mechanisms of T cells, NK cells, B cells, and myeloid cells in pancreatic cancer or studying the effects of pro-inflammatory (such as IL-6, TNF-α) or anti-inflammatory factors (such as IL-10, TGF-β) secreted by PBMCs on tumor progression.

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