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Species | Human |
Cat.No | ABC-TC4331 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Mononuclear Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Peripheral Blood |
Disease | Pancreatic Cancer |
Storage | Liquid Nitrogen |
Product Type | Diseased Human Peripheral Blood Mononuclear Cells |
Human Pancreatic Cancer Peripheral Blood Mononuclear Cells are primarily derived from the peripheral blood of pancreatic cancer patients. They are a mixed cell population separated from the blood by density gradient centrifugation, including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are generally round or oval. In the tumor microenvironment, these cells can participate in anti-tumor or tumor-promoting processes by secreting cytokines (such as IL-6, TNF-α) and mediating immune responses, among which regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSCs) may facilllitate immune escape.
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Human Pancreatic Cancer Peripheral Blood Mononuclear Cells can be used to study the tumor immune microenvironment, such as evaluating the activity and immunosuppressive mechanisms of T cells, NK cells, B cells, and myeloid cells in pancreatic cancer or studying the effects of pro-inflammatory (such as IL-6, TNF-α) or anti-inflammatory factors (such as IL-10, TGF-β) secreted by PBMCs on tumor progression.