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Human Pancreatic Type 1 Diabetic Islets of Langerhans

Product Name

Human Pancreatic Type 1 Diabetic Islets of Langerhans

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Cat.No

ABC-H0093X

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.

Disease

Type 1 Diabetic

Source Organ

Islet

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
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Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Islets of Langerhan

Growth Mode

Adherent

Product Type

Pancreatic Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are Human Pancreatic Type 1 Diabetic Islets of Langerhans, and how are they obtained?

    These are clusters of pancreatic cells isolated from individuals with Type 1 Diabetes. They include beta cells, which are responsible for insulin production, and are typically obtained from donor pancreatic tissue through enzymatic digestion and density gradient centrifugation.

  • What are primary research applications for Human Pancreatic Type 1 Diabetic Islets of Langerhans?

    These islets are used in research focused on Type 1 Diabetes, including studies on insulin production, beta-cell function and regeneration, autoimmune mechanisms, and the development of new diabetes treatments.

  • How do Human Pancreatic Type 1 Diabetic Islets of Langerhans differ from non-diabetic islets?

    In Type 1 Diabetes, the beta cells in the islets are damaged or destroyed by an autoimmune response, leading to reduced or absent insulin production. This is a key difference compared to non-diabetic islets, which have functioning beta cells.

  • Can Human Pancreatic Type 1 Diabetic Islets of Langerhans be passaged in culture?

    No, Human Pancreatic Type 1 Diabetic Islets of Langerhans cannot be passaged in culture. These are primary cells with a limited lifespan, and they do not proliferate like cell lines. Once isolated, the islets can be maintained in culture for a limited period to study their function, but they will not divide or generate new islets. For ongoing studies, new islets must be isolated from donor tissue.

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