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Primary Cells

Human Perineurial

  • For research use only

Cat No.

ABC-TC3751

Product Type

Nervous Cells

Cell Type

Perineurial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

Human Perineurial from AcceGen Research Laboratories are isolated from human spinal nerves.

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Description

Human Perineurial Cells are primary cells isolated from adult peripheral nerves, specifically from the perineurium—the sheath encasing nerve fascicles. These cells are harvested under sterile conditions to preserve their native characteristics before cryopreservation at early passages. These cells exhibit a characteristic flattened, epithelial-like morphology and form functional tight junctions. They express key barrier and basement membrane proteins, including claudin 1, glucose transporter 1 (GLUT1), and epithelial membrane antigen (EMA/MUC1), reflecting their in vivo role in maintaining the blood–nerve barrier (BNB). They also synthesize basement membrane components, including type IV collagen, laminin, and fibronectin, which are critical for nerve fascicle structural support. These cells are terminally differentiated and should not be passaged continuously. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Perineurial Cells, Human Perineurium Cells, Perineurial Cells, Perineurium Fibroblast-like Cells

Species

Human

Cat.No

ABC-TC3751

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Perineurial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Nervous Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • These Human Perineurial Cells serve as a robust in vitro model for studying peripheral nerve barrier physiology, cellular responses to injury, and the process of perineurial repair. They are also suited for mechanistic assays examining tight-junction remodeling, transepithelial electrical resistance (TEER), molecular permeability, and interaction with Schwann cells or immune infiltrates. In disease modeling, they help elucidate pathogen entry across the nerve sheath, fibrotic scar formation, and the clearance of lipid or protein debris in neuropathies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring Human Perineurial

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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