H9-derived Neural Crest Cells

Description

H9-derived Neural Crest Cells are differentiated from the H9 human embryonic stem cell line through controlled in vitro differentiation protocols. Neural crest cells are multipotent progenitor cells that emerge during embryonic development and give rise to a wide range of cell types, including peripheral neurons, Schwann cells, melanocytes, craniofacial cartilage, and smooth muscle cells. Following differentiation and expansion, the cells are cryopreserved for research applications. H9-derived Neural Crest Cells have been reported to express neural crest-associated markers including SOX10, p75NTR (NGFR), HNK-1, AP2α, and FOXD3. In vitro, these cells exhibit a migratory phenotype and can further differentiate into multiple neural crest-derived lineages under appropriate culture conditions. H9-derived Neural Crest Cells are widely used in developmental biology, stem cell research, disease modeling, regenerative medicine, and neurocristopathy studies. Each lot undergoes rigorous quality control testing and is confirmed to be free of mycoplasma, bacterial, fungal, and yeast contamination.