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Human Periodontal Ligament Fibroblasts

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The periodontal ligament is a connective tissue located between the cementum of teeth and the alveolar bone of the mandibula. It plays an integral role in the maintenance and regeneration of periodontal tissue. The cells responsible for maintaining this tissue are thought to be fibroblasts, which can be either multipotent or composed of heterogenous cell […]
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Periodontal Ligament Fibroblasts
Product Code

HPDLF
Species

Human
Cat.No

ABC-TC3750
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Periodontal Ligament
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Oral Cells
Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Description

Periodontal Ligament Fibroblasts (PLFs) are the predominant cell types found in periodontal ligament and play an important role in development, function and regeneration of periodontal connective tissues. Fibroblasts of periodontal ligament are considered multipotent cells and involved in the synthesis and phagocytosis of collagen and matrix components, secretion of cytokines, as well as osteoclastogenesis. Although similar in morphology and growth rate, periodontal ligament fibroblasts differ functionally from gingival fibroblasts in terms of response towards biological factors, extracellular matrix expression and alkaline phosphatase levels.
Why Choose Human Periodontal Ligament Fibroblasts from AcceGen?
AcceGen human periodontal ligament fibroblasts are isolated from human periodontal tissue. Cells are cryopreserved at passage 1 and delivered on dry ice. Each vial contains more than 5×10^5 cells in 1 ml volume. Human periodontal ligament fibroblasts are negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots . Cells are characterized with expression of fibronectin and vimentin by immunofluorescence. Human periodontal ligament fibroblasts are guaranteed to further expand for 10 population doublings with stable activity and morphology following AcceGen recommended protocols.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • For research use only

  • Human periodontal ligament fibroblasts provide an excellent model for in vitro study of fibroblast related functions, osteoclastogenic properties, periodontal diseases, regenerative medicine and drug response.

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