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Human Peripheral Blood Mononuclear Cells, Fresh

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Human Peripheral Blood Mononuclear Cells are available as positive and negative controls for T-cell monitoring in ELISPOT, ELISA, cytokine bead array, tetramer/pentamer, and flow cytometry assays. A peripheral blood mononuclear cell is defined as any blood cell with a round nucleus. These blood cells are a critical component in the immune system to fight infection […]
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Species

Human

Cat.No

ABC-TC3727

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Normal Human Peripheral Blood Mononuclear Cells

Description

Human Peripheral Blood Mononuclear Cells (PBMCs), Fresh are mononuclear cell populations isolated from healthy human peripheral blood, which are enriched from whole blood by density gradient centrifugation (e.g., Ficoll-Paque).Primary cells, freshly isolated, typically not cultured or passaged. PBMCs mainly include lymphocytes (T cells, B cells, NK cells) and monocytes. PBMCs are the core executors of innate and adaptive immune responses: T/B cells mediate specific immunity, NK cells exert killing functions, and monocytes can differentiate into macrophages or dendritic cells, participating in antigen presentation and inflammation regulation. Express common immune markers such as CD3 (T cells), CD19 (B cells), CD56 (NK cells), CD14 (monocytes).Their abnormal activation or dysfunction is associated with a variety of diseases, such as T cell overactivation leading to graft-versus-host disease (GVHD), while monocyte infiltration promotes atherosclerotic plaque formation.

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Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human Peripheral Blood Mononuclear Cells (PBMCs), Fresh are widely used in immunology research, including infection (such as HIV, HCV), autoimmune disease (rheumatoid arthritis), tumor immunotherapy (CAR-T development) and vaccine evaluation. PBMCs are an ideal experimental system for investigating immune mechanisms, high-throughput drug screening, and biomarker identification.

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